The present invention relates to a pharmaceutical composition for preventing and ameliorating the symptoms of arthritis or preventing and ameliorating cartilage destruction or chondrocyte death in a subject suffered from arthritis, comprising an effective amount of an active component selected from a compound, a mixture, and a mycelium prepared from Antrodia cinnamomea.本發明關於一種用於預防或改善患有關節炎的個體的關節炎症狀或用於預防或改善患有關節炎的個體軟的骨破壞或軟骨細胞死亡的醫藥組合物，包含有效劑量的活性成份，該活性成份係選自牛樟芝製備的化合物、混合物或菌絲體。
