PASCAL FURET,DARRYL BRYNLEY JONES,ANDREAS MARZINZIK,BAHAA SALEM,JOSEPH SCHOEPFER,WOLFGANG JAHNKE,STEPHANIE KAY DODD,ROBERT MARTIN GROTZFELD,PAUL MANLEY,XAVIER FRANCOIS ANDRE PELLE
申请号：
PT13730652
公开号：
PT2861579T
申请日:
2013.05.09
申请国别(地区):
PT
年份:
2018
代理人:
摘要：
The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention； capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.
