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Substituted chromenes for treatment of fibrosis or non-alcoholic steatohepatitis
专利权人:
OSTEONEUROGEN INC.
发明人:
Byung Soo Youn,Jun Hwan Kim,Han Soo Kim,Ho Sup Yoon,Ik Hwan Kim
申请号:
US16036949
公开号:
US10370364B1
申请日:
2018.07.17
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A compound represented by the following Formula 1 or a pharmaceutically acceptable salt thereof:wherein R1 is a substituted or unsubstituted C1-5 linear or branched alkyl, a C5-6 cycloalkyl, a C5-6 cycloalkyl containing at least one heteroatom selected from among O and N, a substituted or unsubstituted C6-12 aryl, or a C5-6 heteroaryl containing at least one heteroatom selected from among O and N; R2 is hydrogen, ethyl, acetyl, acetoxy, carboxy, benzoyloxy or 3,4,5-trihydroxybenzoyloxy; and R3 to R5 are each independently hydrogen, hydroxyl, methyl, methoxy, acetoxy, carboxy or benzoyloxy.
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