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人工真皮
专利权人:
セントロ・デ・インベステイガイシオネス・エネルゲテイカス,メデイオアムビエンタレス・イ・テクノロヒカス・(セ.イ.エ.エメ.ア.テ.)
发明人:
ホルカノ ノヴアル,ホセ ルイス,ラルシエル ラグヂ,フエルナンド,メアナ インフイエスタ,アルヴアロ,ゴメス ラネス,サラ,デル リオ ネカヴスキー,マルセラ
申请号:
JP2008118300
公开号:
JP5047047B2
申请日:
2008.04.30
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
Artificial dermis (1) obtained from plasma with platelets (2) and human fibroblasts. The plasma with platelets (2) is obtained from the fractionating of total blood (4) from the patient (8) by light centrifugation, and the human fibroblasts (3) from a skin biopsy (5). Clotting is obtained by adding calcium. This artificial dermis (1) provides for the rapid growth of the keratinocytes (6) seeded on its surface to build an artificial skin (7) which can easily be transplanted. Large areas of artificial dermis (1) are obtained from a small skin biopsy (5) and minimal quantities of plasma with platelets (2), which being enriched with cytokines and platelet growth factors, strengthens the proliferation of the cells seeded, both inside and on the surface. The artificial skin (7) obtained can be used to treat major burn treatments, chronic skin ulcers, etc., or be used, by employing genetically altered cells, as a vehicle for gene therapy.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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