Procedure for obtaining a composition that contains growth factors, which comprises the steps of heat-treating a platelet-rich plasma or the supernatant of a platelet-rich plasma that contains released growth factors in order to increase its temperature, for eliminating the complement and reducing the immunoglobulins present therein, and lyophilizing the plasma or supernatant in order to obtain a final dry composition that can easily be transported, handled and stored, thereby facilitating periodic or chronic treatments with blood compounds. It has been shown that when the final dry composition is resuspended, a once again humid composition is obtained that maintains its biological properties intact.procedimiento de obtención de una composición que contiene factores de crecimiento que comprende las fases de: a) disponer de un plasma rico en plaquetas o de un sobrenadante de plasma rico en plaquetas que contiene factores de crecimiento liberados, b) aplicar un tratamiento térmico al plasma rico en plaquetas o al sobrenadante de plasma rico en plaquetas, durante el cual se aumenta la temperatura del mismo, c) liofilizar dicho plasma rico en plaquetas o sobrenadante de plasma rico en plaquetas； donde los pasos de aplicar un tratamiento térmico y de liofilizar se realizan en orden distinto.
