Jose Luis Jorcano Noval,Fernando Larcher Laguzzi,Alvaro Meana Infiesta,Sara Gomez Llanes,Marcela Del Rio Nechaevsky
申请号：
US13367548
公开号：
US09168125B2
申请日:
2012.02.07
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Artificial dermis (1) obtained from plasma with platelets (2) and human fibroblasts. The plasma with platelets (2) is obtained from the fractionating of total blood (4) from the patient (8) by light centrifugation, and the human fibroblasts (3) from a skin biopsy, (5). Clotting is obtained by adding calcium. This artificial dermis (1) permits rapid growth of the keratinocytes (6) seeded on its surface to build an artificial skin (7) which can easily be transplanted. Large areas of artificial dermis (1) are obtained from small amounts of starting materials and can be enriched with cytokines and platelet growth factors, to strengthen proliferation of the cells seeded. The artificial skin (7) obtained can be used to treat major burn treatments, chronic skin ulcers, etc., or be used, by employing genetically altered cells, as a vehicle for gene therapy.
