Regents of the University of Minnesota;Novartis AG
发明人:
SAWCHUK, Ronald J.,CHEUNG, Belinda W.Y.,WALL, G. Michael
申请号:
ES11732210
公开号:
ES2644826T3
申请日:
2011.01.07
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
Methods and materials useful for applying moxifloxacin to the ear are described. The methods involve delivering a composition that contains at least one viscogenic agent and moxifloxacin or a salt thereof to the epidermal surface of the tympanic membrane via the ear canal. The composition is delivered to the tympanic membrane in a flowable form and, after delivery to the tympanic membrane, becomes sufficiently viscous such that the moxifloxacin is localized against the tympanic membrane. Such compositions can be used to prophylactically and/or therapeutically treat middle and inner ear conditions, including otitis media.