REGENTS OF THE UNIVERSITY OF MINNESOTA;NOVARTIS AG
发明人:
SAWCHUK RONALD J,WALL G MICHAEL,CHEUNG BELINDA W.Y
申请号：
ZA201205965
公开号：
ZA201205965B
申请日:
2012.08.07
申请国别(地区):
ZA
年份:
2014
代理人:
摘要：
Methods and materials useful for applying moxifloxacin to the ear are described. The methods involve delivering a composition that contains at least one viscogenic agent and moxifloxacin or a salt thereof to the epidermal surface of the tympanic membrane via the ear canal. The composition is delivered to the tympanic membrane in a flowable form and, after delivery to the tympanic membrane, becomes sufficiently viscous such that the moxifloxacin is localized against the tympanic membrane. Such compositions can be used to prophylactically and/or therapeutically treat middle and inner ear conditions, including otitis media.
