Ronald J. Sawchuk;Belinda W.Y. Cheung;G. Michael Wall
发明人:
Ronald J. Sawchuk,Belinda W.Y. Cheung,G. Michael Wall
申请号:
US13520519
公开号:
US20120289541A1
申请日:
2011.01.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Methods and materials useful for applying moxifloxacin to the ear are described. The methods involve delivering a composition that contains at least one viscogenic agent and moxifloxacin or a salt thereof to the epidermal surface of the tympanic membrane via the ear canal. The composition is delivered to the tympanic membrane in a flowable form and, after delivery to the tympanic membrane, becomes sufficiently viscous such that the moxifloxacin is localized against the tympanic membrane. Such compositions can be used to prophylactically and/or therapeutically treat middle and inner ear conditions, including otitis media.