Pirrolotriazina refers to compounds of formula (i) wherein R1 is phenyl or a bicyclic carbociclo 9 to 10 members optionally substituted with alkyl (c1-c4), cycloalkyl (C3 C6), halogen substituents in Aromatic heterocycle, among others, of 5 to 6 members that I have up to 3 Teroatomos bicyclic Heterocycles, 8 to 10 members optionally substituted alkyl (c1-c4),NO2 substituents, CN, among others, among others R2 is Halogen, alkyl (C1 - C5) or o-alkyl (C1 - C3) R3 is alkyl (C1 - C5), phenyl optionally substituted by Halogen substituents heteroaromatico CN, among others, of 5 to 6 members that have up to two heteroatoms selected o, s or n, halogen Among others, CN, is alkyl R4 (C1 - C5) optionally substituted cycloalkyl (c3-c5), halogen,Phenyl substituents, among others, halogen, CN, a compound of formula (ii) where q is 1 to 3, among others.Preferred compounds are: N - (4 - [4-amino-6 - (methoxymethyl) - 7 - (4 - (methyl) pyrrolo [2,1-f] - 5 - [1,2,4] triazin il] phenyl) - n - [2-fluoro-5 - (trifluoromethyl) phenyl] urea N - (4 - (4 - amino - 4 - (methoxymethyl) - 7 - [(4 metilpiperazin - 1 - yl) methyl] pyrrolo [2,1-f] - 5 - [1,2,4] triazin il} phenyl) - n - [2-fluoro-5 - (trifluoromethyl) Yl] urea, among others. It also relates to a Pharmaceutical composition.These compounds are useful as Kinase Inhibitors in the treatment of hiperproliferativos Disorders such as psoriasis, Breast Cancer, sarcomaSE REFIERE A COMPUESTOS DERIVADOS DE PIRROLOTRIAZINA DE FORMULA (I) DONDE R1 ES FENILO O UN CARBOCICLO BICICLICO DE 9 A 10 MIEMBROS OPCIONALMENTE SUSTITUIDO CON ALQUILO(C1-C4), CICLOALQUILO(C3-C6), HALOGENO, CN, ENTRE OTROS SUSTITUYENTES, HETEROCICLO AROMATICO DE 5 A 6 MIEMBROS QUE TIENE HASTA 3 HETEROATOMOS, HETEROCICLO BICICLICO DE 8 A 10 MIEMBROS OPCIONALMENTE SUSTITUIDOS CON ALQUILO(C1-C4), NO2, CN, ENTRE OTROS SUSTITUYENTES, ENTRE OTROS R2 ES HALOGENO, ALQUILO(C1-C5) U O-ALQUILO(C1-C3) R3 ES ALQUILO(C1-C5) OPCIONALMENTE SUSTITUIDO CON HALOGENO, FENILO, CN, ENTRE OTROS SUS
