A device for sealing a puncture hole in a bodily organ (1), the device comprising an inner member (7) adapted for positioning against an inner surface of the bodily organ; an outer member (10, 20, 30, 40) adapted for positioning against a corresponding outer surface of the bodily organ; and an elongated retaining member (9, 13, 24). The inner member is arranged at a distal end of the elongated retaining member and the outer member is movable along the elongated retaining member. The outer member has a compressible structure, thereby enabling, when in a first state, after having been deployed inside the bodily organ through the puncture hole, retraction of the outer member out of the puncture hole. The outer member, when in a second state, is arranged to be engaged in a locking arrangement with the elongated retaining member such that the outer member can be moved distally along the elongated retaining member and fixed in a locked position at the outer surface of the bodily organ to thereby enabling sealing of the puncture hole by at least one of the inner member and the outer member.