BUDZIK, BRIAN,COOPER, DAVID GWYN,FORBES, IAN THOMSON,GARZYA, VINCENZO,JIN, JIAN,SHI, DONGCHUAN,SMITH, PAUL WILLIAM,WALKER, GRAHAM
申请号：
CA2624504
公开号：
CA2624504C
申请日:
2006.09.27
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Compounds which have activity at M1 receptor and their uses in medicineCompounds of formula (I) and salts and solvates are provided: wherein R4 isfluoro, R5 is selected from hydrogen, halogen, cyano, C1-6alkyl, C1-6alkylsubstituted with one or more fluorine atoms, C1-6alkoxy, and C1-6alkoxysubstituted with one or more fluorine atoms； and R6 is selected from halogen,cyano, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C3-6cycloalkyl, C3-6cycloalkyl substituted with one or more fluorine atoms, C1-6alkoxy and C1-6alkoxy substituted with one or more fluorine atoms, and Q ishydrogen or C1-6alkyl. The compounds are expected to be useful for therapy,for example in the treatment of psychotic disorders and cognitive impairment.
