Thomas J. Troxler;Dominik Feuerbach;Werner Müller;Bernard Lucien Roy;Konstanze Hurth;Mathias Frederiksen
发明人:
Dominik Feuerbach,Werner Müller,Bernard Lucien Roy,Thomas J. Troxler,Konstanze Hurth,Mathias Frederiksen
申请号：
US12907506
公开号：
US08933090B2
申请日:
2010.10.19
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to 1-aza-bicycloalkyl derivatives of Formula (I)； wherein the substituents are as defined in the specification, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them. Formula (I), wherein A represents O or N(R1)； Y represents a group of formula, or wherein the left bond is attached to the A group and the right bond is attached to the R group； R represents a substituted or unsubstituted C5-C10aryl, substituted or unsubstituted hetero-C5-C10aryl, a group N(R1)(R4), or a group N(R2)(CHP3R4)； R represent a hydrogen, C1-C4alkyl, or CF3； R2 represents hydrogen, C1-C4alkyl, or CF3； R3 represents hydrogen, C1-C4alkyl, or CF3； R4 represents a substituted or unsubstituted C5-C10 aryl or a substituted or unsubstituted C5-C10heteroaryl； in free base or acid addition salt form.
