FEUERBACH, DOMINIK,MUELLER, WERNER,ROY, BERNARD LUCIEN,TROXLER, THOMAS J.,HURTH, KONSTANZE,FREDERIKSEN, MATHIAS
申请号：
CA2566155
公开号：
CA2566155C
申请日:
2005.06.17
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to 1-aza-bicycloalkyl derivatives of Formula(I)； wherein the substituents are as defined in the specification, toprocesses for their production, their use as pharmaceuticals and topharmaceutical compositions comprising them. Formula (I), wherein A representsO or N(R1)； Y represents a group of formula, or wherein the left bond isattached to the A group and the right bond is attached to the R group； Rrepresents a substituted or unsubstituted C5- C10aryl, substituted orunsubstituted hetero-C5-C10aryl, a group N(R1)(R4), or a group N(R2)(CHP3R4)；R represent a hydrogen, C1-C4alkyl, or CF3； R2 represents hydrogen, C1-C4alkyl, or CF3； R3 represents hydrogen, C1-C4alkyl, or CF3； R4 represents asubstituted or unsubstituted C5-C10 aryl or a substituted or unsubstituted C5-C10heteroaryl； in free base or acid addition salt form.
