Abouabdellah, Ahmed,Chereze, Nathalie,Fayol, Aude,Lochead, Alistair,Saady, Mourad,Vache, Julien,Yaiche, Philippe
申请号：
AU2010247214
公开号：
AU2010247214B2
申请日:
2010.05.11
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The invention relates to compounds of the general formula (I) where: R2 is a hydrogen or fluorine atom or a hydroxyl, cyano, trifluoromethyl, C1-6-alkyl, C1-6-alkoxy, or NR8R9 group； m, n, o and p independently are a number from 0 to 3, provided that 2&nlE；m+n&nlE；5 and that 2&nlE；o+p&nlE；5； A is a covalent bond, an oxygen atom, a C1-6-alkylene group or a —O—C1-6-alkylene group in which the end that is an oxygen atom is bonded to the R1 group and the end that is an alkylene group is bonded to the carbon of the bicyclic compound； R1 is an optionally substituted aryl or heteroaryl group； R3 is a hydrogen or fluorine atom or a C1-6-alkyl or trifluoromethyl group； R4 is an optionally substituted 5-membered heterocyclic compounds； wherein the compounds can be in the state of a base or an acid addition salt. The invention can be used in therapeutics.
