KARLSSON JAN OLOF G NORWAY,KURZ TINO SWEDEN,ANDERSSON ROLF SWEDEN
申请号：
IN1213/MUMNP/2010
公开号：
IN300732B
申请日:
2008.12.12
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
Compound of general Formula I or a salt thereof for use in the treatment of cancer, wherein X represents CH or N, each R1 independently represents hydrogen or -CH2COR5 R5 represents hydroxy, optionally hydroxylated alkoxy, amino or alkylamido each R2 independently represents a group ZYR6 Z represents a bond, or a C1-3 alkylene or oxoalkylene group optionally substituted by a group R7 Y represents a bond, an oxygen atom or a group NR6 R6 is a hydrogen atom, a group COOR8, an alkyl, alkenyl, cycloalkyl, aryl or aralkyl group optionally substituted by one or more groups selected from COOR8, CONR8 2, NR8 2, OR8, =NR8, =0, OP(O) (OR8)R7 and OSO3M R7 is hydroxy, an optionally hydroxylated, optionally alkoxylated alkyl or aminoalkyl group R8 is a hydrogen atom or an optionally hydroxylated, optionally alkoxylated alkyl group M is a hydrogen atom or one equivalent of a physiologically tolerable cation R3 represents a C1-8 alkylene group, a 1,2- cykloalkylene group, or a 1,2-arylene group, optionally substituted with R7 and each R4 independently represents hydrogen or C1-3 alkyl. WO2009078794A1
