BLEAM MAUREEN,GILMER TONA M,GREGER JAMES G JR,LAQUERRE SYLVIE G,LIU LI
申请号:
IN4325/DELNP/2013
公开号:
IN2013DN04325A
申请日:
2013.05.15
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The disclosure is directed to a method of treating humans suffering from V600 mutant melanoma that incorporates the detection of the presence or absence of at least one mutation in at least one NRAS protein and/or at least one MEK1 protein or a gene encoding said protein and subsequently initiating treatment modifying treatment or discontinuing treatment with a chemotherapeutic agent selected from a BRaf inhibitor or other suitable agent based upon the presence or absence of said mutation.