BLEAM, MAUREEN,GILMER, TONA, M.,GREGER, JAMES, G., JR.,LAQUERRE, SYLVIE, G.,LIU, LI
申请号：
SG2013035233
公开号：
SG190689A1
申请日:
2011.11.18
申请国别(地区):
SG
年份:
2013
代理人:
摘要：
The disclosure is directed to a method of treating humans suffering from V600 mutant melanoma that incorporates the detection of the presence or absence of at least one mutation in at least one NRAS protein and/or at least one MEK1 protein, or a gene encoding said protein, and subsequently initiating treatment, modifying treatment, or discontinuing treatment with a chemotherapeutic agent selected from a BRaf inhibitor or other suitable agent based upon the presence or absence of said mutation.
