JAMES G. GREGER JR.,LI LIU,MAUREEN BLEAM,SYLVIE G. LAQUERRE,TONA M. GILMER
申请号：
BR112013012485
公开号：
BR112013012485A2
申请日:
2011.11.18
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The disclosure is directed to a method of treating humans suffering from V600 mutant melanoma that incorporates the detection of the presence or absence of at least one mutation in at least one NRAS protein and/or at least one MEK1 protein, or a gene encoding said protein, and subsequently initiating treatment, modifying treatment, or discontinuing treatment with a chemo-therapeutic agent selected from a BRaf inhibitor or other suitable agent based upon the presence or absence of said mutation.
