James G. Greger;Li Liu;Sylvie G. Laquerre;Tona M. Gilmer;Maureen Bleam
发明人:
Maureen Bleam,Tona M. Gilmer,James G. Greger,Sylvie G. Laquerre,Li Liu
申请号：
US13988116
公开号：
US20130231347A1
申请日:
2011.11.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The disclosure is directed to a method of treating humans suffering from V600 mutant melanoma that incorporates the detection of the presence or absence of at least one mutation in at least one NRAS protein and/or at least one MEK1 protein, or a gene encoding said protein, and subsequently initiating treatment, modifying treatment, or discontinuing treatment with a chemo-therapeutic agent selected from a BRaf inhibitor or other suitable agent based upon the presence or absence of said mutation.
