Ramesh C. Gupta,Radha Munagala,Farrukh Aqil,Jeyaprakash Jeyabalan
申请号：
US15910322
公开号：
US20180185285A1
申请日:
2018.03.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A composition is provided that comprises a therapeutic agent encapsulated by a milk-derived microvesicle. The compositions can include therapeutic agents such as phytochemical agents or chemotherapeutic agents, while the milk-derived microvesicle can be derived from raw milk or colostrum. Further provided are methods for isolating a microvesicle that includes the steps of obtaining an amount of milk, and subjecting the milk to a series of sequential centrifugations configured to yield greater than about 300 mg of microvesicle protein per 100 ml of milk. Methods of modifying an immune response and treating a cancer in which a milk-derived microvesicle composition is administered are also provided.
