The present invention relates to a combination comprising (a) RAD001, or a pharmaceutically acceptable salt thereof, and (b) BEZ235, or pharmaceutically acceptable salt thereof, for simultaneous, separate or sequential use for enhancement of an immune response； a pharmaceutical composition comprising such combination； a method of enhancing immune response in a subject comprising administration of said combination to a subject in need thereof； use of such combination for preparation of a medicament for the enhancement of an immune response； and a commercial package thereto.
