Reivindicaci n 1 Un compuesto de f rmula (1) en la que R est seleccionado de hidr geno halo alquilo haloalquilo hidroxialquilo alcoxialquilo (alcoxi) alcoxialquilo ((cicloalquil) alcoxi) alquilo (cicloalcoxi) alquilo haloalcoxialquilo (haloalcoxi) alcoxialquilo ((halocicloalquil) alcoxi CON (R) (R)((AR1) tar) pyridazole, or halogenated benzene zimidazolo, provided that R 1 is hydrogen r83099, not tar； R2 should be selected from halogen, phenyl or tetrahydrogen isotopes and replaced by one of r8311 and 0-3 substitutes selected from halogen, tar, halogen, alcoxi and halogen； e If R2 is halogen, R1 and R83099, it is not asphalt at the same time； R 3 is selected from Azetidini, Pirrolidini, Piperidinilo, Piperazinilo, Piperazinilo or Homoridinilo, and 0-3 is used instead of halogen or asphalt； R830808 is selected from asphalt or halide； R83099 is selected from hydrogen or asphalt； Halogen, hydroxy, hydroxy,alkoxy, alkoxyalkyl, (alkoxy) alkoxyalkyl, (((alkoxy) alkoxy) alkoxy) alkyl, ((benzyloxy) alkoxy) alkyl, ((R¹⁰) (R¹¹) N) alkyl or (R⁶) alkyl； with the proviso that R¹ and R⁵ are not simultaneously alkyl； R⁶ is selected from (oxetanyl) alkyl, ((oxetanyl) alkoxy) alkyl, (tetrahydropyranyloxy) alkyl, (tetrahydropyranyl) alkoxy) alkyl, ((pyrrolidinonyl) alkoxy) alkyl, (Ar¹O) alkyl, ((Ar¹) alkoxy) alkyl, ((Ar²) alkoxy) alkyl, (oxetanyl) oxy, ((R⁸) (R⁹) N) alkoxy, alkylthio, alkylsulfonyl or (R⁸) (R⁹) N； R⁷ is selected from (Ar¹) alkyl, (Ar¹) alkoxy, N-alkoxycarbonyl or ((Ar¹) alkyl) HNCO； or R⁷ is selected from pyrimidinyl,benzofuropyrimidinyl or pyrazolopyrimidinyl substituted with 0-1 alkyl substituents； R⁸ is selected from hydrogen, alkyl, (cycloalkyl) alkyl, alkoxyalkyl, (tetrahydropyranyl) alkyl, tetrahydropyranyl or alkoxyphenyl； R⁹ is selected from hydrogen or alkyl； or (R⁸) (R⁹) N taken together is selected from azetidinyl, pyrrolidinyl, piperidinyl, (spirocyclobutyl) piperidinyl, piperazinyl, morpholinyl, thiomorpholinyl or dioxidothiomorpholinyl, and is substitut
