LAKSHMINARAYANA VOGETI,WEIHE ZHANG,V. SATISH KUMAR,YARLAGADDA S. BABU,PRAVIN L. KOTIAN
申请号：
ARP160103021
公开号：
AR106241A1
申请日:
2016.09.30
申请国别(地区):
AR
年份:
2017
代理人:
摘要：
Claim 1: compound (1) represented by formula,Or a salt that can be accepted from a drug perspective, in which case, each case is independent: R1 stands for - OH - or758080,-NH832222,-NHRᶜ,-No. 7580； - No. 74966；1. Asphalt, arilo, aralquilo, straight, straight, straight, halogen, halogen, ring, tar (cycloquil) asphalt, - C (o) r758080；-C (O) OH -C (O) OR-OC (O) R-C (O) NH-C (O) NHR-C (o) No. 7580； (r74966)；-NHC (O) R o -NR C (O) ROr the combination of two R1 gem cases and the carbon represented represents - C (o) -；Or two adjacent or R1 Gemini are combined to form a fused carbon ring or heterocyclic ring or alternative ring； W is a link, - C (o) NH -,-C (O) N (R) --That's it.-CH - o -C (O) -R represents arilo, heterosexual, aralquilo, heterosexual, cycloquilo, heterosexual (cyclopropyl) tar or (heterosexual) alternative tar； V represents alternative arilo or heterosexual； Z is not or represents one or more alternatives independent of the halogenated, halogenated-no832222 class；-CN -C (O) R-C (O) OH -C (O) OR-OC (O) R-C (O) NH-C (O) NHR-C (o) No. 7580； (r74966)；-NHC (O) R-N (R) C (O) R-OS (O) (R)-NHS (o) - 8346； (r758080) and - NR 7580； (s) (o) 8346； (r758080)；X stands for - C (nh8322) -,-C (NH (R)) --C (No. 7580)；-C (NHS (O) R) --C (NHC (O) R) --C (NHC (O) NH) -C (NHC (O) NHR) --C (NHC (o) No. 7580； r74966) -,-C (OH)-C (i.e. (TAR) -,-C (No. 832323) -,-C (CN) --C (No. 832222) -,-C (S (O) R) --C -C (3DO) R -C -C (3DO) NR R --C -C (3DO) SR --C -S (O) R --C -S (O) R --C S (O) (OR) --C -S (O) (OR) --C -SO NR R --C (halogen) -,-C (personnel)-C (cyclopropyl) tar,-C (alquenil) --C (TAR) - O-C (aralquil) -；R3 is an alternative arilo, heteromorphic, cyclopropyl or isocyclopropyl compound； R3 74919 does not or represents one or more alternatives, whether halogenated, hydroxy, pitch-cf-8323；-OCF8323,alcoxi arilo heteroarilo ariloxi amino aminoalquilo -C (O) NHCyanide, NHC (o) pitch, so-8322-pitch, so8322； nh832222；cicloalquilo - (CH) OR-No.8322；- (CH) NR R- (CH) C (O) R-7491； (C
