KIM, Jun Hwan,LIM, Seyoung,SEO, Minji,CHOI, Hyun Ho,KIM, Dohoon,JU, Mi Kyeong,PARK, Ju-Young,KIM, Seul Gi,LIM, Sangmyoun,KIM, Jong Gyun,NAM, Su Youn,朱美敬,PARK, Ju-Young,朴珠英,KIM, Seul Gi,金瑟吉,LIM, Sangmy
申请号：
HK18116581
公开号：
HK1257373A1
申请日:
2018.12.26
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
The present invention provides a dual function protein prepared by linking a biologically active protein and an FGF mutant protein to an Fc region of an immunoglobulin, which has improved pharmacological efficacy, in vivo duration and protein stability. A dual function protein according to the present invention exhibits improved pharmacological efficacy, in vivo duration and protein stability, and a pharmaceutical composition containing the dual function protein as an active ingredient may be effectively used as a therapeutic agent for diabetes, obesity, dyslipidemia, metabolic syndrome, non-alcoholic fatty liver diseases, non-alcoholic steatohepatitis or cardiovascular diseases.
