Jun Hwan KIM,Seyoung LIM,Minji SEO,Hyun Ho CHOI,Dohoon KIM,Mi Kyeong JU,Ju-Young PARK,Seul Gi KIM,Sangmyoun LIM,Jong Gyun KIM,Su Youn NAM
申请号：
US15768865
公开号：
US20200024318A1
申请日:
2016.10.28
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides a dual function protein prepared by linking a biologically active protein and an FGF mutant protein to an Fc region of an immunoglobulin, which has improved pharmacological efficacy, in vivo duration and protein stability. A dual function protein according to the present invention exhibits improved pharmacological efficacy, in vivo duration and protein stability, and a pharmaceutical composition containing the dual function protein as an active ingredient may be effectively used as a therapeutic agent for diabetes, obesity, dyslipidemia, metabolic syndrome, non-alcoholic fatty liver diseases, non-alcoholic steatohepatitis or cardiovascular diseases.
