KIM, JUN HWAN,LIM, SEYOUNG,SEO, MINJI,CHOI, HYUN HO,KIM, DOHOON,JU, MI KYEONG,PARK, JU-YOUNG,KIM, SEUL GI,LIM, SANGMYOUN,KIM, JONG GYUN,NAM, SU YOUN
申请号：
CA3003115
公开号：
CA3003115A1
申请日:
2016.10.28
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention provides a dual function protein prepared by linking a biologically active protein and an FGF mutant protein to an Fc region of an immunoglobulin, which has improved pharmacological efficacy, in vivo duration and protein stability. A dual function protein according to the present invention exhibits improved pharmacological efficacy, in vivo duration and protein stability, and a pharmaceutical composition containing the dual function protein as an active ingredient may be effectively used as a therapeutic agent for diabetes, obesity, dyslipidemia, metabolic syndrome, non-alcoholic fatty liver diseases, non-alcoholic steatohepatitis or cardiovascular diseases.
