Jun Hwan KIM,Seyoung LIM,Minji SEO,Hyun Ho CHOI,Dohoon KIM,Mi Kyeong JU,Ju-Young PARK,Byung Hyun CHOI,Jun Kyung LEE,Jong Gyun KIM,Su Youn NAM
申请号：
US15768616
公开号：
US20180305428A1
申请日:
2016.10.28
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides a fusion protein comprising an FGF21 mutant protein and an Fc region of an immunoglobulin. The fusion protein according to the present invention exhibits improved pharmacological efficacy, in vivo duration and protein stability, and a pharmaceutical composition comprising the fusion protein as an active ingredient may be effectively used as a therapeutic agent for diabetes, obesity, dyslipidemia, metabolic syndrome, non-alcoholic fatty liver disease or non-alcoholic steatohepatitis.
