The present invention provides antibodies or the antigen-binding portion thereof to a tumor-associate carbohydrate antigen. Also disclosed herein are pharmaceutical compositions and methods for the inhibition of cancer cells in a subject in need thereof. The pharmaceutical compositions comprise an antibody or an antigen-binding portion thereof and at least one pharmaceutically acceptable carrier.本發明係提供針對腫瘤相關醣類抗原之抗體或其抗原結合部位。本文亦揭露抑制有需要的個體體內的癌細胞之醫藥組成物及其使用方法。醫藥組成物包含抗體或其抗原結合部位以及至少一藥學上可接受之載體。