ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO TWO OR MORE ANTIGEN MOLECULES REPEATEDLY

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专利权人:

CHUGAI SEIYAKU KABUSHIKI KAISHA

发明人:

IGAWA, Tomoyuki,ISHII, Shinya,MAEDA, Atsuhiko,NAKAI, Takashi

申请号：

PH12014502054

公开号：

PH12014502054B1

申请日:

2014.09.15

申请国别(地区):

PH

年份:

2015

代理人:

摘要：

It is found that a molecule of an antibody which exhibits a weaker antigen-binding activity at a pH value in an early endosome compared with that at a pH value in a plasma can bind to two or more antigen molecules, and it is also found that the antibody has a long half-life in a plasma and is improved in the period during which the antibody can bind to an antigen.

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中国工程科技知识中心

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http://www.ckcest.cn/home/