ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO TWO OR MORE ANTIGEN MOLECULES REPEATEDLY

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专利权人:

发明人:

IGAWA TOMOYUKI,ISHII SHINYA,MAEDA ATSUH,NAKAI TAKASHI

申请号：

IN7178/DELNP/2010

公开号：

IN2010DN07178A

申请日:

2010.10.11

申请国别(地区):

IN

年份:

2012

代理人:

摘要：

The present inventors discovered that antibodies having weaker antigen-binding activity at the early endosomal pH in comparison with that at the pH of plasma are capable of binding to multiple antigen molecules with a single antibody molecule, have long half-lives in plasma, and have improved durations of time in which they can bind to antigen.

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中国工程科技知识中心

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