Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly

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专利权人:

Chugai Seiyaku Kabushiki Kaisha

发明人:

MAEDA, Atsuhiko,IGAWA, Tomoyuki,NAKAI, Takashi,ISHII, Shinya

申请号：

AU2017279662

公开号：

AU2017279662A1

申请日:

2017.12.20

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

#$%^&*AU2017279662A120180118.pdf#####ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO TWO OR MORE ANTIGEN MOLECULES REPEATEDLY ABSTRACT It is found that a molecule of an antibody which exhibits a weaker antigen-binding activity at a pH value in an early endosome compared with that at a pH value in a plasma can bind to two or more antigen molecules, and it is also found that the antibody has a long half-life in a plasma and is improved in the period during which the antibody can bind to an antigen.

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中国工程科技知识中心

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