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18F-labelled folates
专利权人:
Merck & Cie
发明人:
Groehn, Viola,Ametamey, Simon Mensah,Ross, Tobias Ludwig,Lam, Phoebe,Moser, Rudolf
申请号:
AU2008237930
公开号:
AU2008237930B2
申请日:
2008.04.11
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention is directed towards a new method of synthesis of 18F-folateradiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate)or derivative thereof, through direct radiolabeling with 18 [F] fluoride, aswell as 18F-folate radiopharmaceuticals obtained by such method of synthesisand their use in diagnosis and monitoring of cancer therapy and therapy of inflammatoryand autoimmune diseases.
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