Simon Mensah Ametamey,Rudolf Moser,Tobias Ludwig Ross,Phoebe Lam,Viola Groehn
申请号：
US14797640
公开号：
US10377756B2
申请日:
2015.07.13
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18[F]fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.
