AMETAMEY, SIMON MENSAH,MOSER, RUDOLF,ROSS, TOBIAS LUDWIG,LAM, PHOEBE,GROEHN, VIOLA
申请号:
PL08736117
公开号:
PL2146944T3
申请日:
2008.04.11
申请国别(地区):
PL
年份:
2014
代理人:
摘要:
The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18[F]fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.