Simon Mensah Ametamey;Rudolf Moser;Tobias Ludwig Ross;Thomas Leighton Mindt;Viola Groehn
发明人:
Simon Mensah Ametamey,Rudolf Moser,Tobias Ludwig Ross,Thomas Leighton Mindt,Viola Groehn
申请号:
US12595297
公开号:
US08344140B2
申请日:
2008.04.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked through a triazole- or tetrazole linker to a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.