KALISH VINCENT JACOB,REARDON JOHN,BROOKFIELD FREDERICK ARTHUR,COURTNEY STEPHEN MARTIN,FROST LISA MARIE,TOSCANO JOHN P
申请号:
IN2672/KOLNP/2015
公开号:
IN2015KN02672A
申请日:
2015.08.13
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present disclosure provides nitroxyl donating pharmaceutical compositions comprising N-substituted hydroxylamine derivatives. The compositions are highly efficacious in treating cardiovascular diseases (e.g., heart failure), have a suitable toxicological profile, and are sufficiently stable for intravenous or oral administration.