Vincent Jacob Kalish,John Reardon,Frederick Arthur Brookfield,Stephen Martin Courtney,Lisa Marie Frost,John P. Toscano
申请号:
US16779015
公开号:
US20200163929A1
申请日:
2020.01.31
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure provides nitroxyl donating pharmaceutical compositions comprising N-substituted hydroxylamine derivatives. The compositions are highly efficacious in treating cardiovascular diseases (e.g., heart failure), have a suitable toxicological profile, and are sufficiently stable for intravenous or oral administration.