KALISH, VINCENT JACOB,REARDON, JOHN,BROOKFIELD, FREDERICK ARTHUR,COURTNEY, STEPHEN MARTIN,FROST, LISA MARIE,TOSCANO, JOHN P.
申请号:
CA2898445
公开号:
CA2898445A1
申请日:
2014.01.17
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present disclosure provides nitroxyl donating pharmaceutical compositions comprising N-substituted hydroxylamine derivatives. The compositions are highly efficacious in treating cardiovascular diseases (e.g., heart failure), have a suitable toxicological profile, and are sufficiently stable for intravenous or oral administration.