Vincent Jacob Kalish,John Reardon,Frederick Arthur Brookfield,Stephen Martin Courtney,Lisa Marie Frost,John P. Toscano
申请号：
US16370443
公开号：
US20190224159A1
申请日:
2019.03.29
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present disclosure provides nitroxyl donating pharmaceutical compositions comprising N-substituted hydroxylamine derivatives. The compositions are highly efficacious in treating cardiovascular diseases (e.g., heart failure), have a suitable toxicological profile, and are sufficiently stable for intravenous or oral administration.
