ARVELA, Riina,HEIKKINEN, Terhi,HOLM, Patrik,PRUSIS, Peteris,ROSLUND, Mattias,SALO, Harri
申请号：
ES13779617
公开号：
ES2624873T3
申请日:
2013.09.30
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound of Formula I, ** Formula ** in which A and B form, together with the atoms to which they are attached, ** Formula ** in which atoms marked with * and * 'are linked to the molecular moiety precursor； X is CR5 or N； Y is CR6 or N； Z is CR4 or N, with the proviso that when Y or X is N, then Z is not N； R1 is (C1-C6) alkyl, (C3-C6) cycloalkyl, (C1-C6) haloalkyl, (C1-C6) alkoxy-(C1-C6) alkyl, (C1-C6) haloalkoxy-(C1-C6) alkyl , (C1-C6) alkyl-S-(C1-C6) alkyl, heterocyclyl, heterocyclyl (C1-C3) alkyl, phenyl, phenylalkyl (C1-C3) or phenoxyalkyl (C1-C6), wherein said cycloalkyl ( C3-C6), heterocyclyl or phenyl is unsubstituted or substituted with 1 or 2 substituents, each independently being halogen, (C1-C5) alkyl, halo (C1-C5) alkyl, (C1-C5) alkoxy, (C3-) cycloalkyl C6), CN, haloalkoxy (C1-C5), alkyl (C1-C5) -S-, alkyl (C1-C5) - (S>； = O) -, alkyl (C1-C5) - (O>； = S>； = O) -, (C1-C3) alkylamino or di (C1-C3) alkylamino； R2 is (C1-C6) alkyl； R3 is (C1-C6) alkyl； R4 is H, halogen, (C1-C6) alkyl, (C1-C6) alkoxy, halo (C1-C6) alkyl, halo (C1-C6) alkoxy, (C1-C6) alkoxy (C1-C6) alkoxy, ( C1-C6) -S-, (C1-C6) alkylamino, halo (C1-C6) alkylamino, (C1-C6) alkyl - (C>； = O), CN or heterocyclyl； R5 is H, halogen, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C1-C6) alkoxy, (C1-C6) haloalkyl, (C1-C6) -alkoxy (C1-C6) alkyl, haloalkoxy ( C1-C6), (C1-C6) alkoxy-(C1-C6) alkoxy, (C1-C6) alkyl -S-, (C1-C6) alkyl - (S>； = O) -, (C1-C6) alkyl - (O>； = S>； = O) -, halo (C1-C6) alkyl-S-, halo (C1-C6) alkylamino, (C1-C6) alkyl - (C>； = O) or CN； and R6 is H, halogen, (C1-C6) alkyl or halo (C1-C6) alkyl； or R1 and R6 form, together with the atoms to which they are attached, a saturated or unsaturated 5 or 6 membered heterocyclic ring containing, in addition to the nitrogen atom to which R1 is attached, 0 or 1 additional heteroatom selected from N , O and S, wherein said heterocyclic ring is unsubstituted or substituted with 1 or 2 substituents, each independently being (C1-C2) alky
