НАДЖЕНТ Бенджамин (US),БЕНКО Золтан (US),РЕНГА Джеймс (US),ЛОСО Майкл (US),МАРТИН Тимоти (US)
申请号：
RU2011111548/13
公开号：
RU2011111548A
申请日:
2009.08.25
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. A composition comprising a compound of the general formula:! ! where R1 is! (a) unsubstituted pyrimidinyl, pyridazinyl or pyrazinyl, or! (b) substituted pyrimidinyl, pyridazinyl or pyrazinyl, wherein each substituted pyrimidinyl, pyridazinyl or pyrazinyl contains one or more substituents independently selected from (C2-C6) alkenyl, (C2-C6) alkenyloxy, (C1-C6) alkoxy, ( C1-C6) alkyl, (C2-C6) alkynyl, (C2-C6) alkynyloxy, aryl, (C3-C6) cycloalkenyl, (C3-C6) cycloalkenyloxy, (C3-C6) cycloalkyl, (C3-C6) cycloalkoxy, halogen, halogen (C1-C6) alkyl or heterocyclyl； ! R2 is H, (C2-C6) alkenyl, (C2-C6) alkenyloxy, (C1-C6) alkoxy, (C1-C6) alkyl, (C2-C6) alkynyl, (C2-C6) alkynyloxy, aryl, ( C3-C6) cycloalkenyl, (C3-C6) cycloalkenyloxy, (C3-C6) cycloalkyl, (C3-C6) cycloalkoxy, halogen, halogen (C1-C6) alkyl or heterocyclyl； ! R3 is H, (C2-C6) alkenyl, (C2-C6) alkenyloxy, (C1-C6) alkoxy, (C1-C6) alkyl, (C2-C6) alkynyl, (C2-C6) alkynyloxy, aryl, ( C3-C6) cycloalkenyl, (C3-C6) cycloalkenyloxy, (C3-C6) cycloalkyl, (C3-C6) cycloalkoxy, halogen, halogen (C1-C6) alkyl or heterocyclyl； ! R2 and R3 may optionally form a cycle, where the cycle contains 3 or more atoms, optionally including an O, S or N atom； ! R4 is H, (C2-C6) alkenyl, (C2-C6) alkenyloxy, (C1-C6) alkoxy, (C1-C6) alkyl, (C2-C6) alkynyl, (C2-C6) alkynyloxy, aryl, ( C3-C6) cycloalkenyl, (C3-C6) cycloalkenyloxy, (C3-C6) cycloalkyl, (C3-C6) cycloalkoxy, halogen, halogen (C1-C6) alkyl or heterocyclyl； ! R4 and R2 are optionally joined together to form a 4-, 5- or 6-membered ring with - (CH2) -； ! R5 is NO2, CN, CO2R6, unsubstituted heterocyclyl, substituted heterocyclyl, C (= (O or S)) J (J1) (J2),! where the substituted heterocyclyl contains one or more substituents that are independently selected�1. Композиция, содержащая соединение общей формулы: ! ! где R1 представляет собой ! (а) незамещенный пиримидинил, пиридазинил или пиразинил или ! (b) замещенный пиримидинил, пиридазинил или пиразинил, где каждый замещенный пир
