SEL DE 2-AMINO-2-(HYDROXYMETHYL)PROPANE-1,3-DIOL CRISTALLIN DE L'ACIDE 4-(4-(1 -ISOPROPYL-7-OXO-1,4,6,7-TETRAHYDROSPIRO[INDAZOLE-5,4'-PIPERIDINE]-1 '-CAR BONYL)-6-METHOXYPYRIDIN-2-YL)BENZOIQUE

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专利权人:

PFIZER INC.

发明人:

FERNANDO, DILINIE,LACASSE, SHAWN M.,WIGLESWORTH, KRISTIN

申请号：

CA3082867

公开号：

CA3082867A1

申请日:

2018.11.14

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The invention provides the tris salt of 4-(4-(1-isopropyl-7-oxo-1,4,6,7- tetrahydrospiro[indazole-5,4'-piperidine]-1'-carbonyl)-6-methoxypyridin-2-yl)benzoic acid as a crystalline anhydrous or tri-hydrate； as well as polymorphs, pharmaceutical compositions, dosage forms, and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase (ACC) enzyme(s) in an animal.

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