Crystalline 2-amino-2-(hydroxymethyl)propane-1,3-diol salt of 4-(4-(1-isopropyl-7-oxo-1,4,6,7-tetrahydrospiro(indazole-5,4'-piperidine)-1'-carbonyl)-6-methoxypyridin-2-yl)benzoic acid

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专利权人:

Pfizer Inc.

发明人:

FERNANDO, Dilinie,LACASSE, Shawn M.,WIGLESWORTH, Kristin

申请号：

AU2018372109

公开号：

AU2018372109A1

申请日:

2018.11.14

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The invention provides the tris salt of 4-(4-(1-isopropyl-7-oxo-1,4,6,7- tetrahydrospiro[indazole-5,4'-piperidine]-1'-carbonyl)-6-methoxypyridin-2-yl)benzoic acid as a crystalline anhydrous or tri-hydrate； as well as polymorphs, pharmaceutical compositions, dosage forms, and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase (ACC) enzyme(s) in an animal.

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