4-(4-(1-isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4'-piperidine]-1'-carbonyl)-6-me Crystalline 2-amino-2-(hydroxymethyl)propane-1,3-diol salt of methoxypyridin-2-yl)benzoic acid
The present invention is 4-(4-(1-isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4'-piperidine]-1 as crystalline anhydride or trihydrate. Tris salt of'-carbonyl)-6-methoxypyridin-2-yl)benzoic acid； In addition, it provides polymorphs, pharmaceutical compositions, dosage forms, and their use in the treatment of diseases, conditions or disorders that are regulated by the inhibition of acetyl-CoA carboxylase (ACC) enzyme(s) in animals.본 발명은 결정질 무수물 또는 삼수화물로서의 4-(4-(1-이소프로필-7-옥소-1,4,6,7-테트라히드로스피로[인다졸-5,4'-피페리딘]-1'-카르보닐)-6-메톡시피리딘-2-일)벤조산의 트리스 염； 뿐만 아니라, 다형체, 제약 조성물, 투여 형태, 및 동물에서 아세틸-CoA 카르복실라제 (ACC) 효소(들)의 억제에 의해 조절되는 질환, 병태 또는 장애의 치료에서의 그의 용도를 제공한다.
