Adam Cook,Kevin W. Hunt,Robert Kirk Delisle,Todd Romoff,Christopher T. Clark,Ganghyeok Kim,Christopher P. Corrette,George A. Doherty,Laurence E. Burgess
申请号：
US13141675
公开号：
US08785445B2
申请日:
2009.12.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Compounds of Formula I: (I) in which A, A1, R1, R7a, R7b, R8 and R10 have the meanings given in the specification, are DP2 receptor inhibitors useful in the treatment of useful in the treatment and prevention of immunologic diseases, allergic diseases such as asthma, allergic rhinitis and atopic dermatitis, and other inflammatory diseases mediated by prostaglandin D2 (PGD2). The compounds of Formula I may also be useful in treating diseases or medical conditions involving the Th2 T cell via production of IL-4, IL-5 and/or IL-13.
