COOK ADAM,HUNT KEVIN W,DELISLE ROBERT KIRK,ROMOFF TODD,CLARK CHRISTOPHER T,KIM GANGHYEOK,CORRETTE CHRISTOPHER P,DOHERTY GEORGE A,BURGESS LAURENCE E
申请号:
IN3091/KOLNP/2011
公开号:
IN2011KN03091A
申请日:
2011.07.21
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
(I) in which A, A1, R1, R7a, R7b, R8 and R10 have the meanings given in the specification, are DP2 receptor inhibitors useful in the treatment of useful in the treatment and prevention of immunologic diseases, allergic diseases such as asthma, allergic rhinitis and atopic dermatitis, and other inflammatory diseases mediated by prostaglandin D2 (PGD2). The compounds of Formula I may also be useful in treating diseases or medical conditions involving the Th2 T cell via production of IL-4, IL-5 and/or IL-13.