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NOVOS DERIVADOS DE DI-HIDROQUINOLINA-2-ONA
专利权人:
F.HOFFMANN-LA ROCHE AG
发明人:
申请号:
PT12756741
公开号:
PT2755963T
申请日:
2012.09.12
申请国别(地区):
PT
年份:
2020
代理人:
摘要:
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, A1, A2 and A3 are as described herein, compositions including the compounds and methods of using the compounds. These compounds are useful for therapy or prophylaxis in a mammal, and in particular as aldosterone synthase (CYP11B2 or CYP11B1) inhibitors for the treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism and Cushing syndrome.
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