COOK, ADAM,HUNT, KEVIN W.,DELISLE, ROBERT KIRK,ROMOFF, TODD,CLARK, CHRISTOPHER T.,KIM, GANGHYEOK,CORRETTE, CHRISTOPHER P.,DOHERTY, GEORGE A.,BURGESS, LAURENCE E.
申请号:
CA2748099
公开号:
CA2748099C
申请日:
2009.12.18
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Compounds of Formula I: (I) in which A, A', R1, R7a, R7b, R8 and R10 have themeanings given in the specification,are DP2 receptor inhibitors useful in the treatment of useful in the treatmentand prevention of immunologic diseases, allergic diseasessuch as asthma, allergic rhinitis and atopic dermatitis, and otherinflammatory diseases mediated by prostaglandin D2(PGD2). The compounds of Formula I may also be useful in treating diseases ormedical conditions involving the Th2 T cell viaproduction of IL-4, IL-5 and/or IL-13.