In vivo methods of monitoring biodistribution

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专利权人:

Stephen Henry

发明人:

Bovin, Nikolai Vladimirovich,Henry, Stephen,Korchagina, Elena Yurievna,Rodionov, Igor Leonidovich,Tuzikov, Alexander Borisovich

申请号：

AU2012226647

公开号：

AU2012226647B2

申请日:

2012.02.09

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

Functional-lipid constructs of the structure F-S-L are disclosed, wherein F comprises a tyrosine or histidine residue, S is a spacer covalently linking F to L and L is a lipid. The functional residue may be iodinated and used to radiolabel a biological entity with 1251 and the iodinated constructs are used in a non-invasive method of monitoring the distribution of a biological entity

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